Manchester City and Tottenham Hotspur will face off in an all-Premier League clash after being draw together in the Champions League quarterfinals on Friday.
Manchester United, who staged a dramatic comeback against Paris Saint-Germain to make the last eight, will take on Barcelona in the other headline tie.
Ajax will meet Cristiano Ronaldo’s Juventus after dumping out European champions Real Madrid in the last 16, while Liverpool face Porto.
Ajax Amsterdam v Juventus
Liverpool v Porto
Tottenham Hotspur v Manchester City
Barcelona v Manchester United