Defending champions Bechem United will face Berekum Chelsea in an all premier league tie in the Round of 16 of the MTN FA Cup competition.
The Live draw which was held at the M Plaza hotel in Accra also saw big sides Asante Kotoko and Hearts handed second tier opponents in this round.
Hearts of Oak will face Accra-based division one side Young Wise while Asante Kotoko will host Wassaman FC at the BabaYara Stadium.
Previous winners Medeama SC and Elmina Sharks will also face each other in another all top flight sides game to be played in Tarkwa.
The matches have been scheduled to be played between June 16-18.
Below are the matches for the Round of 16: